組胺酸脫羧酶

出自維基百科,自由嘅百科全書
跳去: 定向搵嘢

組胺酸脫羧酶(學名histidine decarboxylase,減筆HDC)係一種,佢夾埋維他命乙,將組胺酸轉成組織胺二氧化碳[1][2][3]。過程如下:

C₆H₉N₃O₂C₅H₉N₃ + CO₂

組胺酸脫羧酶將組胺酸轉成組織胺

人嘅遺傳基因當中,收埋咗造組胺酸脫羧酶嘅圖樣。 [4][5]

生理上,組織胺係隻重要嘅神經傳遞neutrotransmission),胃酸分泌,平滑肌舒張,都係靠佢。要有組織鞍,就要靠左旋組胺酸脫羧酶( L-histidine decarboxylase),將組鞍酸化成組織鞍。[4]

組織胺亦負責擴大組織通道,畀白血球過去打仗。如果組織胺太多,就會襲擊身體各處發炎,即係敏感症好似哮喘濕疹。其中一個醫法,就係唔畀組胺酸脫羧酶造咁多組織胺。例如食五羥黃酮嘅嘢,係制呢隻酶。

生嘅有唔少組胺酸,如果無住,佢周圍嘅組胺酸脫羧酶,就發揮功用,將佢哋變成組織鞍。人食咁多組織鞍,就打亂身體反應,就好似過敏症,中晒毒咁。有啲魚肉零舍多組胺酸,唔過唔可以做魚生

[編輯]

  1. Epps HM. Studies on bacterial amino-acid decarboxylases: 4. l(-)-histidine decarboxylase from Cl. welchii Type A. Biochem. J. 1945, 39 (1): 42–6. PMC 1258146. PMID 16747851. 
  2. Riley WD, Snell EE. Histidine decarboxylase of Lactobacillus 30a. IV. The presence of covalently bound pyruvate as the prosthetic group. Biochemistry. 1968.October, 7 (10): 3520–8. PMID 5681461. 
  3. Rosenthaler J, Guirard BM, Chang GW, Snell EE. Purification and properties of histidine decarboxylase from Lactobacillus 30a. Proc. Natl. Acad. Sci. U.S.A. 1965.July, 54 (1): 152–8. PMC 285813. PMID 5216347. 
  4. 4.0 4.1 Entrez Gene: histidine decarboxylase. 
  5. Bruneau G, Nguyen VC, Gros F, Bernheim A, Thibault J. Preparation of a rat brain histidine decarboxylase (HDC) cDNA probe by PCR and assignment of the human HDC gene to chromosome 15. Hum. Genet. 1992.November, 90 (3): 235–8. PMID 1487235. 

參攷[編輯]

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