組胺酸脫羧酶

來自維基百科
跳去導覽 跳去搵嘢

組胺酸脫羧酶（學名histidine decarboxylase，減筆HDC）係酶一種，佢夾埋維他命乙，將組胺酸轉成組織胺同二氧化碳[1][2][3]。過程如下：

C₆H₉N₃O₂ → C₅H₉N₃ + CO₂

組胺酸脫羧酶將組胺酸轉成組織胺

人嘅遺傳基因當中，收埋咗造組胺酸脫羧酶嘅圖樣。 [4][5]

生理上，組織胺係隻重要嘅胺，神經傳遞（neutrotransmission），胃酸分泌，平滑肌舒張，都係靠佢。要有組織鞍，就要靠左旋組胺酸脫羧酶（ L-histidine decarboxylase），將組鞍酸化成組織鞍。[4]

組織胺亦負責擴大組織通道，畀白血球過去打仗。如果組織胺太多，就會襲擊身體各處發炎，即係敏感症好似哮喘同濕疹。其中一個醫法，就係唔畀組胺酸脫羧酶造咁多組織胺。例如食五羥黃酮嘅嘢，係制呢隻酶。

生嘅魚肉有唔少組胺酸，如果無冰住雪住，佢周圍嘅組胺酸脫羧酶，就發揮功用，將佢哋變成組織鞍。人食咁多組織鞍，就打亂身體反應，就好似過敏症，中晒毒咁。有啲魚肉零舍多組胺酸，唔醃過唔可以做魚生。

註[編輯]

  1. ↑ Epps HM (1945). "Studies on bacterial amino-acid decarboxylases: 4. l(-)-histidine decarboxylase from Cl. welchii Type A". Biochem. J. 39 (1): 42–6. PMC 1258146. PMID 16747851.
  2. ↑ Riley WD, Snell EE (1968). "Histidine decarboxylase of Lactobacillus 30a. IV. The presence of covalently bound pyruvate as the prosthetic group". Biochemistry. 7 (10): 3520–8. PMID 5681461. {{cite journal}}: Unknown parameter |month= ignored (help)
  3. ↑ Rosenthaler J, Guirard BM, Chang GW, Snell EE (1965). "Purification and properties of histidine decarboxylase from Lactobacillus 30a". Proc. Natl. Acad. Sci. U.S.A. 54 (1): 152–8. PMC 285813. PMID 5216347. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: 作者名單 (link)
  4. ↑ 4.0 4.1 "Entrez Gene: histidine decarboxylase".
  5. ↑ Bruneau G, Nguyen VC, Gros F, Bernheim A, Thibault J (1992). "Preparation of a rat brain histidine decarboxylase (HDC) cDNA probe by PCR and assignment of the human HDC gene to chromosome 15". Hum. Genet. 90 (3): 235–8. PMID 1487235. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: 作者名單 (link)

參攷[編輯]

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出面網頁[編輯]

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