造血幹細胞
造血幹細胞 (HSCs) 係 幹細胞[1]嘅一種，佢可以分化成其它嘅血細胞，所以我地嗌佢造血幹細胞，而呢個分化嘅過程就叫做造血。[2] 嚮脊椎動物度, 最初嘅造血幹細胞起源嚮胚胎主動脈嘅腹側內皮壁，即係妊娠中期嘅主動脈（生殖腺）中腎區域入便，透過一個叫做內皮向造血過渡嘅過程產生。[3][4] 而對於大人, 造血嘅地方喺紅骨髓, 即係嚮大部份骨嘅中間，而紅骨髓係嚮胚胎嘅中胚層度發跡嘅。
攷
[編輯]- ↑ Monga I, Kaur K, Dhanda S (March 2022). "Revisiting hematopoiesis: applications of the bulk and single-cell transcriptomics dissecting transcriptional heterogeneity in hematopoietic stem cells". Briefings in Functional Genomics. 21 (3): 159–176. doi:10.1093/bfgp/elac002. PMID 35265979.
- ↑ Birbrair A, Frenette PS (April 2016). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. PMC 4938003. PMID 27015419.
- ↑ Dzierzak E, Bigas A (May 2018). "Blood Development: Hematopoietic Stem Cell Dependence and Independence". Cell Stem Cell. 22 (5): 639–651. doi:10.1016/j.stem.2018.04.015. hdl:10230/36965. PMID 29727679.
- ↑ Ottersbach K (April 2019). "Endothelial-to-haematopoietic transition: an update on the process of making blood". Biochemical Society Transactions. 47 (2): 591–601. doi:10.1042/BST20180320. PMC 6490701. PMID 30902922.