The film opens in springtime, about a year after Charlotte has died. Her three daughters, Nellie, Aranea, and Joy, are now in the stages of adolescence, with Wilbur serving as a companion and mentor. Templeton has his own children to look after, and Gwen the Goose has just hatched new goslings.
During this time, Wilbur befriends Cardigan, a newborn lamb who is looked down upon by the other lambs and the younger sheep of his flock because he has black wool. Wilbur takes Cardigan under his wing and shows him the farm, the ways of animal life, and dangers for which to look out. However, after only a few weeks, Mr. Zuckerman suddenly sells Cardigan to another farmer, Mr. Hirsh, so Wilbur, along with Nellie, Aranea, Joy, and Templeton, sets out to visit Cardigan and make sure he is doing alright at his new home. Templeton requires Wilbur to babysit his bratty children in return for guidance.
On the journey to visit Cardigan, however, Wilbur is hungry so he gets some blackberries which make him look purple. He then gets his foot tangled in some brambles, which Templeton frees him from (under the promise that Wilbur will babysit Templeton's children for an additional two weeks). Some bark from the trees comes and lands on Wilbur's head. This makes him look like a wild boar. A near hit by a truck then reveals that two other men have now seen Wilbur. Wilbur eventually makes it to Cardigan's, and the two are happy to see each other. After Cardigan tells Wilbur that Mr. Hirsh plans to shear him, Wilbur promises Cardigan that he will stay until the shearing is done.
Meanwhile, an evil fox named Farley comes and steals a hen from the barn, and Wilbur reluctantly tries to stop him after being encouraged by Nellie. However, Wilbur is unsuccessful, as Farley flees from the barn before Mrs. Hirsh arrives, and she sees Wilbur and thinks he was the one after the chickens. Fern notices that Wilbur has disappeared and alerts her uncle Mr. Zuckerman, while Wilbur requests that Nellie and her sisters spin a message in their webs like their mother Charlotte did before she died. However, after trying all night to spin a message, the three spiders fail to spin a message, and Wilbur is chased off by Mrs. Hirsch once again. Wilbur thus abandons his promise to stay with Cardigan, much to Cardigan's dismay. Meanwhile, Farley comes back and attempts to raid the chicken coup once again, but it has been fenced. Farley then sees Cardigan and steals him from the barn, planning to eat him. Wilbur now must save his friend, and does so by trapping Farley in a "pig web". Nellie, Aranea, and Joy spin the word "fox" in a spider web, and Fern arrives just in time to save Wilbur. Farley, while not shown, is most likely disposed of. Aranea and Joy decide to stay with Cardigan, and the film ends as Wilbur fulfills his promise to babysit Templeton's children, to his dismay.
- "It's Not So Hard To Be A Pig"
- "Watch Out Wilbur the Pig!"
- "It's Good To Be Me"
- "Charlotte's Kids"